Sunitinib Malate Capsules Sutinat 50
Trade Name: Sutinat 50
Manufacturer:Natco Pharma Ltd
Presentation: Capsules
Strength: NA
Introduction of Sunitinib Malate Capsules Sutinat
Sunitinib Malate Capsules Sutinat, sold under the brand name Sutinat, is a prescription medication used to treat specific types of cancer. It is a targeted therapy for a class of drugs called tyrosine kinase inhibitors (TKIs).
Composition and Strength
- Active ingredient: Sunitinib maleate
- Available strengths: Usually offered in 12.5 mg, 25 mg, and 50 mg capsules.
Mechanism of Action
Sunitinib Malate Capsules Sutinat works by inhibiting several tyrosine kinases involved in tumor growth and angiogenesis (forming new blood vessels that nourish tumors). By blocking these enzymes, the drug reduces cancer cell proliferation and reduces the blood supply necessary for tumor survival and growth.
Indications
Sunitinib Malate Capsules are used to treat:
- Renal cell carcinoma (RCC): advanced kidney cancer.
- Gastrointestinal stromal tumors (GIST): tumors occurring in the digestive tract, especially when resistant to imatinib.
- Pancreatic neuroendocrine tumors (pNETs): advanced or metastatic pancreatic cancer.
Dosage and Administration
- The dosage depends on the patient’s condition, body weight, and the overall treatment plan prescribed by the healthcare provider.
- It is usually taken orally, once a day, with or without food.
- Treatment schedules often involve alternating periods of treatment and rest (for example, four weeks of treatment, followed by two weeks of rest).
Side Effects of Sunitinib Malate Capsules Sutinat
Common side effects include:
- Fatigue
- Nausea
- Diarrhea
- Loss of appetite
- Changes in skin color
- Hand-foot syndrome (redness, pain, and swelling in the palms and soles)
Serious side effects may include high blood pressure, cardiovascular problems, bleeding, and liver toxicity. Regular monitoring by a healthcare professional is important during treatment.
Precautions
- Patients with a history of liver or cardiac problems should use this drug with caution.
- It is not recommended for use during pregnancy or breastfeeding due to potential harm to the baby.
- Regular blood tests are needed to monitor organ function and adjust the dosage.
Storage
- Store at room temperature, away from direct sunlight and moisture.
- Keep out of reach of children.
Export and Availability
Sunitinib Malate Capsules Sutinat, exported by Rizochem Pharmaceuticals, is available globally in countries like the UAE, Oman, Qatar, Myanmar, Saudi Arabia, Netherlands, Albania, Saint Lucia, Jordan, Romania, South Africa, and more. The product complies with international quality standards and is offered at competitive prices to ensure access to life-saving medication.
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