What is the purpose of the Maximune 500mg Tablet?
To treat human immunodeficiency disease (HIV) defilement Maximune 500mg Tablet is used with ritonavir (Norvir) and various drugs. Protease inhibitors, similar to saquinavir, are a kind of remedy. It works by lessening the amount HIV in the dissemination framework.
Is the antiviral drug Maximune 500mg Tablet a protease inhibitor?
Helps: The principal protease inhibitor to be endorsed by the Food and Medication Organization (FDA) for use related to at least one unidentified nucleoside analog is saquinavir, showcased by Hoffmann-LaRoche under the brand name Invirase.
What are the different functional groups in Saquinavir Mesylate?
The aspartic corrosive subsidiary saquinavir is made through formal
buildup of the super amino gathering of aspartic corrosive (2S,3R)
N(2) carboxy bunch on – 3-hydroxy-1-phenylbutazone-2-arylamine (- quinoline-2-ylcarbonyl)
-L-asparagine. A protease inhibitor for HIV-1. To know more click here.
Is the drug Maximune 500mg Tablet still in use?
This Tablet was embraced for use in the US in 1995 and is still commonly used for the neutralization and treatment of HIV sickness in adults and children in the mix with other antiretroviral remedies.
Is saquinavirTablet an inhibitor that is competitive or non-competitive?
Darunavir and the artificially comparable amprenavir showed blended-type cutthroat uncompetitive hindrance in the motor investigation of wild-type and freak protease, while saquinavir exhibited serious restraint.
Maximune has how many stereogenic centers?
This Tablet has six chiral focuses, bringing about 64 expected stereoisomers; be that as it may, only one stereoisomer is picked for the business detailing. The dynamic substance is combined in a multi-step technique..
Is Saquinavir Mesylate considered a prodrug?
Blend, strength, and against HIV movement of HIV protease inhibitors produced using diglycerides or amino acids, like saquinavir, indinavir, and nelfinavir.
How did Maximune 500mg Tablet come to be?
Saquinavir Improvement: PC helped judicious plan approaches were utilized to make saquinavir, a progress stage partner of a HIV proteinase cleavage site. It’s an exceptionally specific HIV-1 and – 2 proteinase inhibitor, with antiviral viability at 1000-overlap lower fixations than those that cause cytotoxicity.
What is Maximune 500mg Tablet method of action?
Maximune 500mg Tablet is a peptide-like substrate simple that ties to the dynamic site of a protease and keeps it from working. Restraint of saquinavir blocks the cleavage of viral polyproteins, which prompts the production of youthful, noninfectious infection particles.
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