Linezolid IP 100mg 5ml LINOFIT D/S (With Water)


Trade Name:LINOFIT D/S (With Water)

Manufacturer:Zydus Cadila Healthcare Ltd.

Presentation: tablets


Linezolid IP 100mg 5ml What is it? What is the mechanism of action?

Linezolid IP 100mg 5ml  Synthetic antibiotic linezolid (Zyvox) works well against bacteria including Enterococcus faecium, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes, and others.
It works well against isolates of Staphylococcus aureus that are immune to other antibiotics.
By preventing bacteria from producing proteins, linezolid stops bacteria from proliferating. Linezolid does not affect protein synthesis in humans since it differs from bacterial synthesis in both organisms.

What are the purposes of tablets of Linezolid IP 100mg 5ml ?

These infections are treated with linezolid:

Nosocomial pneumonia brought on by methicillin-susceptible and -resistant isolates of Staphylococcus aureus or Streptococcus pneumoniae.
Streptococcus pneumoniae or Staphylococcus aureus-related community-acquired pneumonia (methicillin-susceptible isolates only)
infections of the skin and skin structures, both complicated and simple, like infections in diabetic feet.
infection with Enterococcus faecium that is vancomycin resistant.

What side effects does linezolid have?

Linezolid frequently causes the following adverse effects:

  • Anemia.
  • diarrhoea.
  • vomitinz.
  • headache, and nausea

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What is the linezolid dosage?

For complex skin and skin structure infections or pneumonia, an adult should take 600 mg orally or intravenously every 12 hours for 10 to 14 days.
Treatment for simple infections of the skin and skin structure involves 400 to 600 mg taken orally every 12 hours for 10 to 14 days.
For vancomycin-resistant Enterococcus faecium infections, the recommended dosage is 600 mg administered orally or intravenously every 12 hours for 14 to 28 days.

What other medications or dietary supplements affect linezolid?

A monoamine oxidase inhibitor is linezold (MAOI). This indicates that linezolid prevents the oxidation of substances that monoamine oxidase enzymes ordinarily oxidise. This raises the concentrations of these substances in the body and may raise the possibility of negative side effects. Patients who are using monoamine oxidase inhibitors (MAOI) or who have taken an MAOI within two weeks shouldn’t take linezolid.

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