Clopidogrel Asprin Clopiklot A Tablets

Trade Name: Clopiklot A

Manufacturer: Biochem Pharmaceutical Industries

Presentation: Tablets

StrengthAspirin (75mg) + Clopidogrel (75mg)

Clopidogrel Asprin Clopiklot A is a combined medicine containing clopidogrel and aspirin as active ingredients. This formulation is widely used in the prevention and management of cardiovascular diseases, especially to reduce the risk of heart attack and stroke. The dual action of clopidogrel, a platelet aggregation inhibitor, and aspirin, an antiplatelet agent makes it effective in preventing blood clots.

Key Features:

  1. Active Ingredients:
    • Clopidogrel: A thienopyridine derivative that blocks the P2Y12 ADP receptor on platelets, thereby reducing platelet activation and aggregation.
    • Aspirin: Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, thereby preventing the formation of thromboxane A2, which is important for platelet aggregation.
  2. Therapeutic Uses:
    • Prevention of myocardial infarction (heart attack).
    • Reducing the risk of ischemic stroke.
    • Management of unstable angina or acute coronary syndrome.
    • Post-percutaneous coronary intervention (PCI) and stent placement to prevent stent thrombosis.
  3. Dosage Form:
    • Generally available in tablet form for oral administration.
  4. Strengths:
    • The strength of clopidogrel and aspirin can vary depending on the prescription. Common combinations include clopidogrel 75mg + aspirin 75mg or clopidogrel 75mg + aspirin 150mg.

Benefits of Clopidogrel Asprin Clopiklot A Tablet

  • Dual antiplatelet therapy (DAPT) provides prevention of thrombotic events.
  • Reduces the risk of recurrent cardiac events.
  • Widely studied and recommended in international cardiology guidelines.

Precautions and Side Effects of Clopidogrel Asprin Clopiklot A

  • Precautions:
    • Not recommended for patients with active bleeding or a history of hemorrhagic stroke. 
    • Use with caution in patients with peptic ulcer disease, hepatic impairment, or bleeding disorders.
  • Side Effects:
    • Common: nausea, abdominal discomfort, and mild bleeding.
    • Rare but serious: severe gastrointestinal bleeding, thrombocytopenia, or allergic reactions.

Conclusion:

Clopidogrel Asprin Clopiklot A Tablet is an important medicine in the management and prevention of cardiovascular and thrombotic disorders. By inhibiting platelet aggregation, it significantly reduces the risk of life-threatening events such as heart attack and stroke. Always use this medicine under medical supervision, follow the prescribed dosage, and monitor for side effects.

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