What is the purpose of bortezomib 2 mg Injection?
The medication bortezomib 2 mg Injection is used to treat multiple myeloma (a type of cancer of the bone marrow). Bortezomib is also used to treat mantle cell lymphoma patients (fast-growing cancer that begins in the cells of the immune system). Bortezomib belongs to the class of medicines known as antineoplastic agents.
What is the purpose of bortezomib in the treatment of multiple myeloma?
Bortezomib has been proven to induce responses in previously resistant individuals (including those with poor-risk cytogenetics) and to result in improved progression-free and overall survival in relapsed patients when compared to dexamethasone therapy alone, thanks to its unique mode of action.
What are the bortezomib side effects?
- The injection site may cause dizziness
- lack of appetite
- or pain/redness.
- Common adverse effects include nausea, vomiting, and diarrhea. Your doctor may recommend medication to prevent or alleviate nausea, vomiting, or diarrhea in some circumstances. For more details Click Here.
What is the maximum amount of time you can take Bortezomib?
If you’ve already received myeloma treatment, you can have bortezomib on its own. Bortezomib is commonly taken twice a week for two weeks. After that, you get a ten-day rest. A treatment cycle is a three-week period of treatment.
Is bortezomib an oral medication?
According to data from a mid-stage study presented at the 54th Annual Meeting of the American Society of Hematology in Atlanta, Georgia, the investigational oral proteasome inhibitor MLN9708—which is a new version of Velcade® (bortezomib)—may be more effective and well-tolerated than Velcade injections.
What is the best way to inject bortezomib?
By gently pulling the plunger down with your index finger, inject the bortezomib solution into the fatty tissue of your tummy. Slowly push the plunger of the syringe down the barrel until it can no longer go any further. Count to ten while holding on to the fatty tissue. Then take the needle out of your skin and let go of the pinch.
What is the composition of bortezomib?
Bortezomib is l-phenylalanine amide with a 1-(dihydroxyboranyl)-3-methyl butyl group at the amide nitrogen and a pyrazin-2-ylcarbonyl group at N(alpha). It’s a dipeptidyl boronic acid that inhibits the 26S proteasome in a reversible manner.