Abacavir Abhope tablets
Trade Name: Abhope
Manufacturer: Macleods Pharmaceuticals Pvt. Ltd
What is the abacavir tablet’s purpose?
To treat human immunodeficiency virus (HIV) infection, abacavir is combined with other drugs. Abacavir belongs to the nucleoside reverse transcriptase inhibitor family of drugs (NRTIs). It reduces HIV levels in the bloodstream.
Is Abhope a type of antiretroviral medication (ARV)?
Abhope is a nucleoside reverse transcriptase inhibitor, which is a type of medication (NRTIs). This type of antiviral stops the HIV enzyme reverse transcriptase from copying the virus’s genetic code into a form that can be introduced into human cells.
What is the efficacy of abacavir?
According to the effectiveness analysis, after 24 months of monitoring with abacavir treatment, 91 percent of patients had HIV-1 RNA levels of less than 50 copies/mL, according to the effectiveness analysis.
What are the tenofovir side effects?
- Tenofovir has the potential to induce adverse effects. If any of these symptoms are severe or do not go away, contact your doctor:
- I have diarrhea.
- headache, depression rash, sitting, fever.
- Trouble falling or staying asleep
What is abacavir’s most common adverse effect?
Hypersensitivity (allergic) reaction (see the previous section), nausea, headache, diarrhea, loss of appetite, weariness, lack of energy, and fever are the most common adverse effects of abacavir (high temperature).
What are the abacavir contraindications?
- ABACAVIR should not be taken by anyone.
- A high triglyceride level in the blood
- Lactic acid levels are elevated, resulting in increased blood acidity.
- Coronary artery disease (CAD) affects the blood vessels in the heart.
- An issue with the liver
- illness that is severe.
- for a patient who is breastfeeding and producing milk.
- HLA-B *57:01 gene positivity. To know more click here.
What is abacavir’s mechanism of action?
Phosphorylation of abacavir produces active metabolites that compete for viral DNA integration. They function as a chain terminator of DNA synthesis by competitively inhibiting the HIV reverse transcriptase enzyme.
Is it possible to take tenofovir for an extended period of time?
In most cases, HIV treatment lasts a lifetime. Even if you are feeling well, keep taking tenofovir on a regular basis as directed by your doctor. This will help to maintain the health of your immune system.
What is the best time to discontinue taking tenofovir?
“Stopping [tenofovir] for at least 3.5 years appears to be safe in HBeAg-negative patients with undetectable HBV DNA,” the researchers found, emphasizing that tenofovir can be reintroduced if necessary.
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