Imipenem and Cilastatin Injection 1g I Nem
Trade Name: I Nem
Manufacturer: Glenmark Pharmaceuticals Ltd
Presentation: Injection
Strength: 1g
Imipenem and Cilastatin Injection 1g I Nem
Imipenem and Cilastatin Injection powerful antibiotic combinations used to treat severe bacterial infections. It contains 500 mg of imipenem and 500 mg of cilastatin.
Mechanism:
- Imipenem: Inhibits bacterial cell wall synthesis.
- Cilastatin: Prevents degradation of Imipenem in the kidneys.
Indications:
- Respiratory tract infections
- Urinary tract infections
- Intra-abdominal infections
- Gynecological infections
- Septicemia
- Bone and joint infections
- Skin and soft tissue infections
- Endocarditis
Dose: Usually 500 mg intravenously every 6-8 hours. Adjust for renal impairment.
Contraindications: Hypersensitivity to components or other beta-lactam antibiotics.
Side Effects
- Common: Nausea, vomiting, diarrhea, rash, injection site reactions.
- Serious: Seizures, allergic reactions, pseudomembranous colitis.
Storage: Refrigerate at 2°C to 8°C. Do not freeze.
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