What is fludarabine phosphate used for?
fludarabine phosphate is indicated for the treatment of adult patients with B-cell chronic lymphocytic leukemia (CLL) who have not responded to or whose disease has progressed during treatment with at least one standard alkylating-agent containing regimen.
What drug class does Fludacel belong to?
Medication class: Fludacel is a cancer-fighting chemotherapeutic drug (sometimes known as “antineoplastic” or “cytotoxic”). This medication is known as an “antimetabolite.” (For more details, see the “How this Medication Works” section below.)
What are the side effects of cytarabine?
- The drug cytarabine has the potential to cause side effects. If any of these symptoms are severe or do not go away, see your doctor:
- Irritable bowel syndrome (IBS) and weight loss
- ulcers in the mouth and sores in the throat
- Hair loss is a very prevalent problem.
- musculoskeletal or joint pain
When you take fludarabine, how long does it last in your system?
Non-lymphoma, Hodgkin’s hairy cell leukemia, cutaneous T-cell lymphoma, and acute myeloid leukemia have all been treated with it. Fludarabine is mostly eliminated by the kidneys and has a plasma half-life of about 10 hours.
What is fludarabine’s mechanism of action?
Fludarabine is an anti-cancer medication that is used to treat chronic lymphocytic leukemia. It inhibits DNA synthesis and kills cancer cells by interacting with DNA polymerase alpha, ribonucleotide reductase, and DNA primase.
Is it true that fludarabine causes mucositis?
Myelosuppression (neutropenia, thrombocytopenia, and anemia), fever and chills, lethargy, weakness, infection, pneumonia, cough, nausea, vomiting, and diarrhea are all common side effects. Malaise, mucositis, and anorexia are all common side effects.
Fludarabine is a purine analog, right?
The most often used purine analog is fludarabine, which is used as a first-line treatment for chronic lymphocytic leukemia. Fludarabine also has a strong immunosuppressive effect and is utilized in nonmyeloablative hematopoietic cell transplantation regimens.
Is capecitabine an anti-cancer drug?
Capecitabine is a chemotherapeutic drug. It can be used to treat a variety of cancers, including bowel cancer. Capecitabine can be taken alone or in combination with other chemotherapy medicines. It’s also possible that you’ll get it after radiotherapy.