Dacarbazine Injection 200mg Dacarex
Trade Name: Dacarex
Manufacturer: Alkem Laboratories Ltd
Presentation: Injection
Strength: 200mg
What is Dacarbazine Injection 200mg utilized for?
Dacarbazine Injection 200mg has a place with the gathering of prescriptions called alkylating specialists. It is utilized to treat diseases of the lymph framework and threatening melanoma (a sort of skin malignant growth). It might likewise be utilized to treat different sorts of malignant, not entirely settled by your doctor.
How does dacarbazine help disease?
Dacarbazine has a place with a gathering of chemotherapy drugs called alkylating specialists. It works by adhering to the malignant growth cell’s DNA and harming it. DNA is the hereditary code that controls all that the cell does. Assuming that the DNA is harmed, the disease cell can’t separate and make more malignant growth cells.
Does dacarbazine cause go bald?
Spewing may endure for 12 hours. Brief going bald may happen. Ordinary hair development ought to return after treatment with DTIC-Dome has finished.
How frequently is Dacarbazine Injection 200mg given?
Dacarbazine is directed in an everyday portion of 375 mg/m2 body surface region i.v. like clockwork in a mix with doxorubicin, bleomycin, and vinblastine (ABVD routine).
What are the risks of using Dacarbazine Injection 200mg?
- Dacarbazine has the potential to cause adverse effects. Assuming any of these side effects are extreme or don’t disappear, contact your primary care physician:
- nausea.
- vomiting.
- a lack of appetite
- diarrhea.
- mouth sores and throat sores
- Hair loss is a common occurrence.
- On the face, there is a consuming or shivering sensation.
- flushing.
Does Dacarbazine Injection 200mg cross blood cerebrum obstruction?
Dacarbazine (DTIC) gives a mean reaction pace of 21% on instinctive localisations lymphoma, however, doesn’t cross the blood mind hindrance (BBB). Neither do the organic reaction modifiers like Interleukin 2 which prompts a 25% reaction rate in spread melanoma.
Dacarbazine Injection 200mg is a form of chemotherapy.
Type of medication: Dacarbazine is an anti-cancer chemotherapeutic medication (sometimes known as “antineoplastic” or “cytotoxic”). This drug is referred to as an “alkylating agent.”
What is the mechanism of dacarbazine’s action?
The specific mechanism of dacarbazine’s effect is unknown. Its main mechanism of action is alkylation. Dacarbazine is converted to 5-(3-monomethyl-1-triazolyl)-1H-imidazole-4-carboxamide by liver microsomal enzymes (MTIC). Generating carbonium ions prevents DNA and RNA synthesis.
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