Cisatracurium Besylate Injection

Trade Name: Cisaish

Manufacturer: Aishwarya Healthcare

Presentation: Injection

Strength: Cisatracurium Besylate (20mg/10ml)

Mechanism of Action

Cisatracurium works by blocking the transmission of nerve impulses at the neuromuscular junction, causing muscle relaxation. It competes with acetylcholine for binding sites on nicotinic receptors of the motor end-plate, thereby preventing muscle contraction.

Cisatracurium Besylate Injectionis commonly used to

  • Facilitate endotracheal intubation during surgery.
  • Provide muscle relaxation during mechanical ventilation in critically ill patients.
  • Assist in various types of surgery, particularly those requiring muscle paralysis.
  • Dosage and Administration: The dosage of Cisatracurium Besylate Injection varies depending on the procedure, patient weight, and other factors such as the use of other anesthetic agents. It is administered via vein, the dosage is carefully titrated to achieve the desired level of muscle relaxation.

Side Effects

Potential side effects may include bradycardia, hypotension, bronchospasm, and, rarely, allergic reactions. Due to its muscle-relaxing effects, patients should be monitored closely, particularly for respiratory function.

Storage and Stability

Cisatracurium Besylate Injection should be stored in a refrigerator at 2°C to 8°C. It is stable for a limited period when exposed to room temperature, but prolonged exposure should be avoided.

Precautions

Careful monitoring is needed in patients with cardiac diseases or electrolyte imbalances. It is also important to have resuscitation equipment readily available because of the potential for serious side effects.

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