Asparaginase 10000IU Injection Onconase

To treat acute lymphocytic leukemia, Asparaginase 10000IU Injection erwinia chrysanthemi is used with other chemotherapy drugs (ALL; a type of cancer of the white blood cells).

Asparaginase 10000IU Injection is administered as a shot into a big muscle (intramuscular or IM). The medication may need to be divided into two injections, depending on your dose. As an infusion, it can also be delivered into the vein (intravenous or IV). Because this procedure carries a higher risk of an allergic reaction, a test dose is usually administered first.

Asparaginase 10000IU Injection Erwinia chrysanthemi is an anticancer drug made from an asparaginase-specific enzyme produced from Erwinia chrysanthemi. It acts by diminishing the reserves of asparagine, an essential amino acid involved in DNA synthesis and cell survival in malignant cells, resulting in cell death.

The enzyme l-asparaginase (EC 3.5. 1.1) catalyzes the hydrolysis of asparagine into l-aspartic acid and ammonium. This enzyme is found in a variety of organisms, including bacteria, plants, and some animals, including the serum of some rodents, but it is not found in humans.

The average response time was 21 days. The median time it took for a patient to progress was 63 days (111 days for dogs achieving a complete response and 42 days for dogs achieving a partial response).

According to published research, Erwinia asparaginase should be given three times weekly at a dose of at least 20,000 IU/m2 by IV or IM.

Asparaginase is a commonly utilized enzyme in the pharmaceutical and food sectors. Asparaginase is mostly produced by E. coli, with spectrila being a novel recombinant version of the enzyme.

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