How is vinorelbine injection administered?

The recommended dose of NAVELBINE is 30 mg/m2 given once a week as a vinorelbine injection or infusion over 6 to 10 minutes in combination with cisplatin 120 mg/m2 on Days 1 and 29 and subsequently every 6 weeks.

What is the purpose of vinorelbine injection?

vinorelbine injection is used to treat non-small cell lung cancer (NSCLC) that has spread to neighboring tissues or other sections of the body, both alone and in conjunction with other drugs. Vinorelbine belongs to a group of drugs known as vinca alkaloids.It works by slowing or stopping the growth of cancer cells in the body.

What is the best way to give an IV vinorelbine injection?

Vinorelbine 10 mg/ml concentrate for infusion can be given as a slow bolus (6-10 minutes) after dilution in 20-50 ml sodium chloride 9 mg/ml (0.9 percent) solution for injection or glucose 50 mg/ml (5 percent) solution for injection, or as a short infusion (20-30 minutes) after dilution in 125 ml sodium chloride 9 mg/ml (0.9 percent) solution for injection.

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Is it true that vinorelbine causes hair loss?

Vinorelbine may cause modest, transient hair loss when administered alone. It can, on rare occasions, result in complete hair loss.

What is the source of vinorelbine?

Vinorelbine is a type of chemotherapeutic medication known as a plant alkaloid. Alkaloids derived from plants are known as plant alkaloids. The periwinkle plant produces vinca alkaloids (Catharanthus rosea). Taxanes are derived from the Pacific Yew tree’s bark (Taxus).

Is it true that vinorelbine causes constipation?

This medicine can produce severe constipation, which can lead to death from bowel blockage, intestinal rips, or gut tissue death. If you have constipation, rectal pain, or rectum bleeding, call your doctor straight away. If the medicine spills from the vein, it may cause tissue injury.

What is the purpose of cyclophosphamide?

Cyclophosphamide is a chemotherapy drug that is used to treat cancers of the ovaries, breast, blood, lymph, and nerves (mainly in children). Cyclophosphamide is also used to treat retinoblastoma (an eye disease that primarily affects children), multiple myeloma (a bone marrow cancer), and mycosis fungoides (tumors on the skin).

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