Triptorelin 11.25mg Injection

Triptorelin 11.25mg Injection is a synthetic analog of gonadotropin-releasing hormone (GnRH) used primarily in the treatment of hormone-sensitive conditions. The 11.25mg formulation of Triptorelin is typically given via injection and is designed for long-term therapeutic use. 

Triptorelin is commonly indicated for:

• Prostate Cancer: It helps manage advanced prostate cancer by suppressing testosterone production, which can promote the growth of cancer cells.
• Endometriosis: It is used to treat endometriosis by lowering estrogen levels and reducing associated symptoms.
• Uterine Fibroids: Triptorelin can reduce the size of fibroids and manage symptoms such as heavy bleeding.
• Precocious Puberty: It is used to delay the onset of puberty in children who show early signs of sexual development. 

Triptorelin works by binding to GnRH receptors in the pituitary gland, causing a temporary increase in the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). However, long-term administration results in down-regulation of these receptors, leading to decreased levels of sex hormones (testosterone in men and estrogen in women).

The standard dose for adults is usually one injection of 11.25 mg every three months, depending on the specific condition being treated. The injection is usually given intramuscularly. 

Common side effects may include:

• Hot flashes
• Mood changes
• Fatigue
• Decreased libido
• Injection site reactions (pain, swelling, redness)

Serious side effects can occur, but these are less common, such as allergic reactions or significant mood changes.

Patients should inform their healthcare provider about any pre-existing conditions, especially a history of cardiovascular problems or mood disorders. Triptorelin should be used with caution in patients with osteoporosis, as it may affect bone density over time.

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