Methylene Blue Injection 1.0% Problu 10
Trade Name:–Problu 10
What process breaks down Methylene Blue Injection?
Methylene Blue Injection, a reducing agent of oxidised haemoglobin, transforms the ferric ion (fe+++) back to its oxygen-carrying ferrous state (fe++), which is how methylene blue operates in methemoglobinemia. Methylene Blue, a selective inhibitor of P, is used as an antimalarial drug.
How is Problu 10 broken down?
To treat methemoglobinemia, methylene blue reacts with red blood cells to create leukomethylene blue, which reduces oxidised haemoglobin and returns the ferric ion (fe+++) to its oxygen-carrying ferrous state (fe++). Methylene Blue, a particular P inhibitor, is used as an antimalarial medication.
How is Problu 10 administered through injection?
To stop a local high concentration of the substance from forming more methemoglobin, methylene blue (methylene blue injection) must be administered intravenously very slowly over a period of several minutes. Never go beyond the suggested dosage.
What purpose does Methylene Blue Injection chloride serve?
The counterion of methylene blue is 3,7-bis(dimethylamino)phenothiazin-5-ium, which is an organic chloride salt. An everyday dye with anti-inflammatory, anti-malarial, antidepressant, and cardioprotective effects. It plays the part of an EC 1.4.
What are Methylene Blue Injection’s 1.0% side effects?
- lips, fingernails, or palms that are blue.
- tarry urine
- having trouble breathing
- feeling lightheaded or dizzy.
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What is the Methylene Blue Injection half-life?
With a half-life of 5 to 6.5 hours, methylene blue is eliminated in the urine anywhere from 4 to 24 hours after treatment.
Is Methylene Blue Injection blue a form of medication?
Although just a few studies have calculated methylene blue’s minimum inhibitory concentration (MIC), the gold standard for gauging antimicrobial activity, it has been established that the substance has antibacterial capabilities.
Methylene blue: does it damage kidneys?
However, it has been shown that this medication causes unfavourable side effects in a number of organs, including the kidney and the lymphoid organs. It has been hypothesised that the CsA has harmful effects because it stimulates the generation of oxygen free radicals.
Can you give IV methylene blue?
Through an IV, methylene blue is delivered into a vein. You will receive this injection from a healthcare professional. It may take up to 30 minutes to finish the IV infusion. While you are receiving methylene blue, your respiration, blood pressure, oxygen levels, kidney function, and other vital signs will be constantly monitored.
Methylene blue: is it dangerous?
When taken in therapeutic amounts (2 mg/kg), methylene blue is a medication that is safe. But at excessive levels, it can be hazardous.
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