Why is mesna used in conjunction with Ifosfamide and Mesna Injection?
The Ifosfamide and Mesna Injection acts as a barrier to protect your bladder from discomfort and bleeding. Ifosfamide is always given with Mesna. The majority of people who receive cyclophosphamide treatment do not receive dosages high enough to cause bladder hemorrhage. They won’t necessitate the use of mesna.
What medicine should be used with ifosfamide at all times?
Ifosfamide injection is indicated for use in third-line chemotherapy of germ cell testicular cancer in combination with certain other approved antineoplastic medicines. It should be taken with mesna for the prevention of hemorrhagic cystitis.
Is mesna a type of chemotherapy?
Mesna is a type of chemoprotective agent. Chemoprotective agents are medications that are used in conjunction with some types of chemotherapy to protect the body from or reduce the negative effects.
What are the adverse effects of Ifosfamide and Mesna Injection?
- Side effects that are common
- An increased chance of contracting an infection.
- Breathlessness and a pallid appearance
- Bruising, bleeding gums or nosebleeds are all possible symptoms.
- Fatigue and exhaustion (fatigue) during and after therapy.
- Having a sick feeling of being unwell.
- Irritable bowel syndrome (IBS) is characterized by a loss of appetite.
- Hair thinning.
- The bladder and kidneys are irritated.
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What is an Ifosfamide and Mesna Injection, and how does it work?
Mesna is used to lower the risk of hemorrhagic cystitis (a bladder irritation that can lead to significant bleeding) in people who are taking ifosfamide (a medication used for the treatment of cancer). Mesna belongs to the cytoprotectant class of drugs.
What is the best way to administer an Ifosfamide and Mesna Injection?
At the time of ifosfamide delivery and 4, and 8 hours after each dose of ifosfamide, MESNEX injection is given as intravenous bolus injections in a dosage equivalent to 20% of the ifosfamide dosage weight by weight (w/w). MESNEX’s total daily dose is 60 percent of that of ifosfamide.
Is leucovorin the same as folic acid?
Leucovorin is another name for folic acid. It looks a lot like folic acid, but it’s not the same thing. Folic acid is an over-the-counter dietary supplement for low folate levels, whereas leucovorin is a prescription-only medicine that addresses methotrexate and other anti-folate pharmaceutical adverse effects.
What is the mesna effect, and how does it work?
Mesna is used to lower the risk of hemorrhagic cystitis (a bladder irritation that can lead to significant bleeding) in people who are taking ifosfamide (a medication used for the treatment of cancer).