Denosumab Solution Injection 120mg/1.7ml Esentra

Trade Name:Esentra

Manufacturer: Intas Pharmaceuticals

Presentation: injection


What is the purpose of Denosumab Solution Injection?

In some breast cancer or prostate cancer patients who have a high risk of fracturing bones Denosumab Solution Injection is also prescribed under the trade name Prolia to improve bone mass. In some people with osteoporosis who are at a high risk of fracturing bones, it is also utilised as a treatment.

What kind of medicine is denosumab used for?

Men and women who will be taking corticosteroid medications for at least 6 months, have an increased risk of fractures, are unable to take other medication treatments for osteoporosis, or did not respond to those treatments are treated for osteoporosis that is caused by corticosteroid medications with denosumab injection (Prolia).

What affects bones does denosumab have?

Osteoclast activity is regulated by a protein called RANKL, which is the target of denosumab’s action. This strengthens the bone by preventing the breakdown of bone cells.

What are the negative effects of a 120 mg/1.7 ml Denosumab Solution Injection?

  • Xgeva common side effects
  • Pain in the muscles, joints, or bones (musculoskeletal).
  • aching in the limbs
  • painful nerves
  • Constipation.
  • Rash.
  • infection in the urinary system.

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Is it safe to take Denosumab Solution Injection?

Denosumab has demonstrated success in increasing bone density and lowering hip and spine fracture rates. However, there is a chance of negative side effects. Denosumab shouldn’t be used by those with compromised immune systems since it can induce serious infections that necessitate hospitalisation (such as heart infections).

How is an injection of Denosumab Solution Injection administered?

Once every six months, denosumab is injected subcutaneously into the thigh, belly, or back of the arm. It can be administered by someone with adequate training in injection procedures, making it suitable for use in primary care.

Does Denosumab Solution Injection lessen achy bones?

According to the patients’ VAS assessments at month 12, the denosumab treatment showed a significant reduction in bone pain. All patients in the non-GCT and GCT groups noticed and reported this reduction, which had an average percent reduction of 56.2 percent and 53.6 percent, respectively.

How soon does denosumab start to work?

Within three days of the injection, denosumab begins to reduce bone turnover. It also lingers in the blood for several months after the patient stops taking the medication.

Can denosumab lead to skeletal pain?

If you have any severe Prolia side effects, such as jaw pain, new or unusual thigh, hip, or groyne discomfort, or bone, joint, or muscle pain, let your doctor know right away.

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