What is Zoledronic 4 mg Injection used for?
Zoledronic 4 mg Injection is used to treat elevated calcium levels in the blood (hypercalcemia), which can occur as a result of cancer. This medicine is also used in conjunction with cancer chemotherapy to treat bone issues associated with multiple myeloma and other cancers that have progressed to the bones (e.g., breast, lung).
Is zoledronic acid a form of chemotherapy?
Zoledronic acid (Zometa) is not a cancer treatment and will not delay or stop cancer from spreading. It can, however, be used to treat bone problems in cancer patients. Bisphosphonates are a type of drug that includes zoledronic acid.
What are the benefits of zoledronic acid?
The activity of osteoclasts is reduced by zoledronic acid. This can assist to relieve pain while also strengthening the bones. It also helps to keep calcium from being lost from the bones. This aids in the normalization of calcium levels in the blood.
Does zoledronic acid affect the heart?
According to a study presented at the American Society for Bone and Mineral Research (ASBMR) 2017 Annual Meeting, held September 8-11 in Denver, Colorado, patients treated with zoledronic acid had a greater risk of heart failure, among other cardiovascular diseases.
Why is zoledronic acid given once a year?
In order to treat osteoporosis, zoledronic acid is administered as an IV infusion once a year. To prevent osteoporosis, it’s also administered as an IV infusion every two years. Zoledronic acid boosts bone density and lowers the risk of non-spine fractures, such as hip fractures.
Why is zoledronic acid given slowly?
Zoledronic acid is injected into one of your veins with a needle. Because the medicine must be administered gradually, your IV tube must remain in place for at least 15 minutes. Zoledronic acid is normally given only once to treat hypercalcemia. To know more click here.
Does zoledronic acid lower the immune system?
Anti-cancer immunity and the effects of ZOL ZOL have dramatic impacts on the immune system, including a multitude of immune cell subsets that express the mevalonate pathway enzymes, resulting in a boost in anti-tumour immunity .
Does zoledronic acid affect kidneys?
In patients with pre-existing renal dysfunction or other risk factors, zoledronic acid has been linked to reports of renal impairment and renal failure. Before each dose, patients should have their renal function checked and be properly hydrated.
How long can you take zoledronic acid?
Follow your doctor’s advice to the letter. Your doctor will decide how long you should take this prescription. Zoledronic acid is usually only taken for 3 to 5 years.
How safe is zoledronic acid?
The safety profile of zoledronic acid was satisfactory, with no drug-related adverse effects. Even in high-risk individuals, ZA treatment enhanced bone health by improving bone mineral density and decreasing bone turnover.
Who should not take zoledronic acid?
Stage 4 CKD (severe) Chronic kidney disease (CKD) stage 5 (failure) renal disease with anticipated kidney function decline. a bone break in the upper leg that happened out of nowhere.
Does zoledronic acid cause bone pain?
Zoledronic acid can induce significant bone, joint, and/or muscular discomfort. This might happen anywhere from one day to several months after you begin taking the medicine. Report these symptoms to your doctor, who can help you come up with pain-relieving techniques.
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