Tortaxel Paclitaxel 260mg Injection

Trade Name: Tortaxel

Manufacturer: Torrent Pharmaceuticals Ltd

Presentation: Injection

Strength: 260mg

What is Tortaxel Paclitaxel 260mg Injection used for?

Tortaxel Paclitaxel 260mg Injection (with polyoxyethylated castor oil) is used to treat breast cancer, ovarian cancer (cancer that starts in the female reproductive organs where eggs are generated), and non-small cell lung cancer (NSCLC) alone or in combination with other chemotherapy drugs.

Which medication should be given before administering paclitaxel?

To avoid serious hypersensitivity responses, all patients should be premedicated before receiving paclitaxel. Dexamethasone 20 mg PO, given between 12 and 6 hours before paclitaxel, and diphenhydramine (or it’s equivalent) 50 mg I.V., are examples of such premedication.

How successful is paclitaxel?

Many of the participants in these studies had previously undergone chemotherapy. Nonetheless, single-agent therapy with weekly paclitaxel has obtained response rates of up to 86 percent, combination therapy has achieved response rates of up to 87 percent, and radiation has achieved response rates of up to 100 percent.

How do you feel after paclitaxel?

During or immediately after therapy, you may experience a minor allergic reaction to paclitaxel. This can result in irritation, a rash, or a flushed face. A severe allergic reaction is quite rare. Breathlessness, swelling of the cheeks and lips, and dizziness are all symptoms.

Why is carboplatin given after paclitaxel?

Taxol (paclitaxel, Paxel) must be administered before carboplatin because carboplatin prevents Taxol from having an effect on cancer cells if it is given first. When Taxol is given before carboplatin, there is little interaction and both agents work as planned. This is known as a scheduling interaction. To know more click here.

Why is paclitaxel used in stents?

Paclitaxel is released from the balloon or stent to prevent the creation of scar tissue in the blood vessel, which can cause the artery to re-obstruct (restenosis).

What is the side effect of paclitaxel?

  • Nausea,
  • vomiting,
  • diarrhoea,
  • mouth sores,
  • muscle/joint discomfort,
  • numbness/tingling/burning hands/feet,
  • flushing,
  • dizziness,
  • or sleepiness are all possible side effects. Tell your doctor right away if any of these symptoms persist or worsen. It is possible that you will experience temporary hair loss. After the therapy, your hair should grow normally again.

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