Ponatinib 45mg Tablets Iclusig

Trade Name: Iclusig

Manufacturer: Ikon Pharma

Presentation: Tablet

Strength: 45mg

What is the purpose of Ponatinib 45mg Tablets?

Ponatinib 45mg Tablets is a drug that is used to treat specific types of cancers of the blood (chronic myelogenous leukemia-CML, acute lymphoblastic leukemia-ALL). It works by delaying or stopping the multiplication of cancer cells. It belongs to the kinase inhibitor class of medicines.

What is the purpose of ponatinib?

Ponatinib is a drug that is used to treat chronic-phase chronic myeloid leukemia (CML) in individuals who have failed at least two other treatments.

What are the Iclusig side effects?

  • ICLUSIG’s most common adverse effects include:
  • A rash on the skin.
  • Joint discomfort.
  • Pain in the stomach area (abdomen).
  • Headache.
  • Constipation.
  • Skin that is parched.
  • Blood pressure that is too high.
  • Tiredness. For more details Click Here.

What is ponatinib hydrochloride and how does it work?

Take note of how the words are spoken.. (poh-NA-tih-nib HY-droh-KLOR-ide) (poh-NA-tih-nib HY-droh-KLOR-ide) A medication used to treat individuals with certain kinds of chronic myelogenous leukemia or acute lymphoblastic leukemia with the Philadelphia chromosome.

What are the effects of tyrosine kinase inhibitors?

Tyrosine kinase inhibitors (TKIs) suppress tyrosine kinases, which are chemical messengers (enzymes). Tyrosine kinases are involved in the transmission of growth signals in cells, therefore inhibiting them prevents the cell from growing and dividing. Cancer growth inhibitors can target one or more types of tyrosine kinase.

What is the efficacy of ponatinib?

In 60% of patients, the initial daily dose of ponatinib was 45 mg, in 38% it was 30 mg, and in 2% it was 15 mg. In comparison to the baseline, 85 percent of patients had a better molecular response after a median of 12 months. Ten of the patients (40 percent) had a deep molecular response.

Ponatinib is a type of medication?

Ponatinib belongs to the class of drugs known as protein tyrosine kinase inhibitors (TKI). Tyrosine kinases are proteins that work as chemical messengers to promote the growth of cancer cells. Ponatinib inhibits and disables a number of protein kinases. It’s referred to as a multikinase inhibitor.

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