Idarubicin 10mg Capsule Zavedos

Trade Name: Zavedos

Manufacturer: Pfizer Ltd

Presentation: Capsule

Strength: 10mg

What factors Zavedos to differentiation syndrome?

Zavedos Differentiation syndrome normally occurs 1 to 2 weeks after beginning treatment, however, it can happen at any time. It’s triggered by the anticancer medications causing a big, quick release of cytokines (immune chemicals) from leukemia cells.

Idarubicin is known by what brand name?

Idarubicin is also known as clindamycin. Idarubicin is also known as clindamycin PFS. When referring to the generic medicine name idarubicin, health care practitioners may use the trade name clindamycin or other names such as idamycin PFS.

How are Idarubicin administered?

IDAMYCIN (idarubicin hydrochloride for injection, USP) should be administered gently into a continuously flowing intravenous infusion. Never administer it intramuscularly or subcutaneously. Extravasation during administration can cause severe local tissue necrosis.

What are Zavedos’ side effects?

  • Cytarabine can have negative side effects.
    Assuming that any of these side effects are extreme or don’t disappear, contact your doctor:
  • nausea, vomiting, or diarrhea.
  • Loss of appetite and stomach pain
  • mouth and throat irritation
  • Muscle or joint pain, hair loss

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How is idarubicin administered?

IDAMYCIN (idarubicin hydrochloride for injection, USP) should be administered gently into a continuously flowing intravenous infusion. Never administer it intramuscularly or subcutaneously. Extravasation during administration can cause severe local tissue necrosis.

Idarubicin is a chemotherapy medication, right?

Idarubicin is a chemotherapeutic medication. It’s used to treat acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) that’s returned after being treated with another chemotherapy agent.

What is the purpose of idarubicin?

Idarubicin is used in combination with other drugs to treat acute myelogenous leukemia (AML; a kind of malignancy of the white blood cells). Idarubicin belongs to the anthracycline class of drugs. It works by decreasing or forestalling disease cell improvement in the body.

What is the treatment for differentiation syndrome?

Because the full-blown illness is life-threatening, preemptive corticosteroid administration at the first symptom or indication suggestive of DS has been the standard of care (Figure 1B). The most common treatment is intravenous injections of dexamethasone at a dose of 10 mg twice daily.

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