Estramustine 140 mg Capsule Xtrant

Trade Name: X-Trant

Manufacturer: Natco Pharma Ltd

Presentation: Capsule

Strength: 140mg

Is estramustine an anti-cancer drug?

Type of medication: Estramustine is an anti-cancer prostate organ (“antineoplastic” or “cytotoxic”) chemotherapy medication that also possesses hormone treatment properties.

What is the purpose of estramustine?

Estramustine is used to treat prostate cancer that has progressed to other places of the body or has worsened. Estramustine belongs to the antimicrotubule agent class of drugs. It works by preventing cancer cells from growing and spreading.

What is Estramustine’s mechanism of action?

It’s a carbamate ester, an organochlorine molecule, and a 17beta-hydroxy steroid. It’s made up of 17beta-estradiol. Estramustine is a type of alkylating agent. The alkylating activity of estramustine is the mechanism by which it functions.

What is irinotecan-based chemotherapy, and how does it work?

Irinotecan is a chemotherapeutic drug. Campto is another brand name for it. It’s a treatment for cancer that began in the intestine (bowel cancer). The colon and the rear passage are included in this rectangle.

Is cabazitaxel associated with hair loss?

It’s possible that you’ll experience temporary hair loss. Normal hair growth should continue after the operation. Many people who use this medicine experience severe negative effects.

Is cabazitaxel a more powerful drug than docetaxel?

According to the findings of the phase III FIRSTANA study, cabazitaxel at two different doses was no better than docetaxel in terms of overall survival (OS) or progression-free survival (PFS) in men with metastatic castration-resistant prostate cancer (mCRPC).

What is the mechanism of action of estramustine?

Estradiol and nitrogen mustard are combined in estramustine. The nitrogen-mustard moiety becomes active in vivo and participates in DNA or other cellular components alkylation. This produces DNA damage in malignant cells that are rapidly proliferating, resulting in cell death and, ideally, tumor reduction.

Cabazitaxel is administered in a variety of ways.

Cabazitaxel injection is a liquid that is delivered intravenously (into a vein) by a doctor or nurse in a medical facility over the course of an hour. It’s normally given every three weeks. During your cabazitaxel injectable treatment, you will need to take prednisone every day.

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