What is the purpose of docetaxel injection?
Docetaxel injection is used to treat some types of sorts of breast, lung, prostate, stomach, and head and neck cancers alone or in combination with other drugs. Taxanes are a type of medication that includes docetaxel injection. It works by halting the growth and spread of cancer cells.
What are the docetaxel dosages?
TAXOTERE 75 mg/m2 supplied intravenously over 1 hour, followed by cisplatin 75 mg/m2 administered over 30-60 minutes every 3 weeks [see Dosage Adjustments During Treatment].
What are the polysorbate 80 negative effects?
Polysorbate 80 has been linked to a variety of systemic reactions (e.g., hypersensitivity, nonallergic anaphylaxis, rash) as well as injection- and infusion-site adverse events (ISAEs; e.g., discomfort, erythema, thrombophlebitis) in pharmacological formulations [3, 35–37].
How long does it take for docetaxel to work? Will I start to feel better?
Two to three days following your therapy, your muscles or joints may ache or become painful. This normally wears off after a few days to a week, although for some people it may stay a little longer. It can be excruciatingly unpleasant, necessitating the use of pain relievers or anti-inflammatory medicines like ibuprofen.
What happens next after docetaxel?
Cabazitaxel (Jevtana) is a drug used to treat advanced prostate cancer in men who have progressed during or after docetaxel treatment (Taxotere). In a single 755-patient research, the safety and efficacy of cabazitaxel (Jevtana) were demonstrated.
What is the target of the docetaxel?
Breast, colorectal, lung, ovarian, gastric, renal, and prostate cancer cells are all cytotoxic to docetaxel. Docetaxel does not hinder entry into the mitotic cycle by blocking the disassembly of interphase microtubules, but it does prevent mitosis by inhibiting mitotic spindle construction.
Do you get hair loss after using docetaxel?
In most cases, you will lose all of your hair. Your eyelashes and eyebrows, as well as other body hair, may fall out. After the first or second treatment, hair loss is common.
Docetaxel is effective at which stage of the disease?
docetaxel injection has significant and wide antineoplastic activities because it binds to and stabilizes tubulin, preventing microtubule disintegration and cell death.