What is the purpose of the medicine Decitabine 50mg Injection?
Myelodysplastic syndrome is treated with Decitabine 50mg Injection (a group of conditions in which the bone marrow produces blood cells that are misshapen and do not produce enough healthy blood cells). Decitabine belongs to a class of drugs known as hypomethylation agents.
How long does decitabine take to work?
The median period for patients to attain any level of remission for either CR or CRH was 2 months in the clinical research (with a range of 0.8 to 4.2 months).
What are some of the drug’s other adverse effects?
- Hair thinning.
- Constipation, diarrhea, stomach pain, upset stomach, vomiting, or a decreased appetite.
- Feeling weak, dizzy, or exhausted.
- Mouth discomfort or sores are common.
- Sleeping problems
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What is the efficacy of Decitabine 50mg Injection?
The combination of decitabine and cag demonstrated good response rates (CR 64.7 percent and ORR 82.4 percent) and few treatment-related side effects (induction mortality 4.4 percent ). Patients who responded had a significantly longer median OS (16 months).
What is the metabolization of Decitabine 50mg Injection?
Its short half-life of 8–30 minutes is due to cytidine deaminase’s fast metabolization in the liver. The only side effect of a dose of 100 mg/m2 given intravenously every 12 hours for 5 days (1000 mg/m2 per course) was dose-dependent myelosuppression with a delayed onset and a protracted course.
What is the purpose of Decitabine 50mg Injection?
Decitabine 50mg Injection is used to treat individuals with certain subtypes of the French-American-British (FAB) myelodysplastic syndrome, such as refractory anemia or chronic leukemia. Azacitidine is a metabolite, which is a kind of medication. It represses the development of disease cells, making them be wiped out.
How is decitabine made?
Because DACOGEN is a cytotoxic medicine, it should be handled and prepared with caution. Aseptically reconstituted DACOGEN with 10 mL Sterile Water for Injection, USP at room temperature (20°C to 25°C). The ultimate concentration of the reconstituted DACOGEN solution is 5 mg/mL after reconstitution.
Decitabine is a chemotherapeutic drug.
DECITABINE is a chemotherapy medication (dee SYE ta been). This medication inhibits cancer cell proliferation. It is used to treat myelodysplastic syndromes in adults.
Decitabine is a type of medication.
Decitabine is an anti-cancer chemotherapeutic medication (sometimes known as “antineoplastic” or “cytotoxic”). Decitabine is a “demethylation” and “antimetabolite” agent.